Evolution of Screening Tests
for GS/Celiac Sprue
•100 A.D. - 1950 -
clinical observation
•1950 -1960’s - response
to gluten free diet, 72-hr fecal
fat, oral xylose test, origins of SB biopsy
•1980 -1990’s - serologic testing
for antigliadin Ab, antiendomysial Ab, antitissue
transglutaminase Ab
•2000’s - fecal testing for Antigliadin Ab and Antitissue
transglutaminase Ab†; Quantitative fecal fat
microscopy for malabsorption†; HLA-DQ typing
† Developed and offered exclusively by
EnteroLab.com